Abstract Since the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in Wuhan, China, in December 2019, Coronavirus - 19 (COVID-19) has become a global pandemic with multiple neurological complications. In December 2020, two vaccines have been approved in the United States for the prevention of COVID-19. We report a case of Guillain-Barre Syndrome (GBS) after receiving the first dose of Pfizer - COVID-19 vaccine. Keywords: neurologic complications, guillain-barre syndrome (gbs), covid-19 vaccine Introduction The first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in Wuhan, China, in December 2019 [1], and in few weeks became a global pandemic. Coronavirus - 19 (COVID-19) predominantly causes respiratory illness with symptoms ranging from mild illness presenting with myalgia, sore throat, cough, fever, anosmia, and diarrhea [1], to more moderate-to-severe symptoms of acute respiratory distress syndrome, multi-organ failure and eventually death. Multiple neurological complications have been associated with COVID-19 infection [2,3]. In December 2020, the FDA approved two vaccines for the prevention of COVID-19 infection. In the clinical trials of the vaccine, multiple side effects have been reported ranging from mild symptoms including but not limited to injection site pain, myalgia, fatigue, and fever to more serious side effects including anaphylactic shock [4,5]. However, Guillain-Barre Syndrome (GBS) after receiving COVID-19 vaccine has not been reported to date (February 2, 2021) to the best of our knowledge. We report the first reported case of GBS after receiving the first dose of Pfizer COVID-19 vaccine.
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